BioActive D-Pearls are small, soft gelatin capsules with 3000 IU (75 µg) vitamin D₃ in each capsule. The vitamin D is dissolved in cold-pressed olive oil to improve absorption in the digestive system as vitamin-D is a fat-soluble vitamin. Their size makes them easy to swallow, but they can also be chewed. Research has shown that D-Pearls have a high absorption in the body.

Documented bioavailability

D-Pearls have been tested by researchers at the University of Oslo who gave athletes different doses of vitamin D in the form of D-Pearls and inactive placebo capsules. The test showed that D-Pearls both in high and low dosage was absorbed well by the participants while the athletes who received placebo, had unchanged vitamin D in the blood.

The illustration shows the difference in vitamin D in the blood during 4 weeks in the group receiving 76 mcg of vitamin D daily and in the group receiving placebo capsules.

Source: Baumann ACK. Effekt av vitamin D-tilskudd på 25(OH)D status. University of Oslo, July 2013.

Vitamin D is a fat-soluble vitamin. This implies that the vitamin need some fat in order to be absorbed in the intestine. Like oher vitamins, vitamin D is essential. There are several kinds of vitamin-D, but the two most important forms are D₂ (ergocalciferol) and D₃ (cholecalciferol). D₃ is the form of the vitamin that is synthesized in the skin when we are exposed to sufficient amounts of sunlight or a similar type of UV-radiation. Vitamin D from sunlight is an effective vitamin D source but is only produced when the sun is high in the sky. In large parts of Europe, this only happens during the summer period, and therefore we can only produce sufficient levels of the vitamin this time of year.

Vitamin D₂ Is only available from the diet. It is produced by certain fungi and plants when they are exposed to ultraviolet light. Both vitamin D₂ and D₃ require subsequent activation in the liver and kidneys in order to become biologically active. Science used to believe that both forms of vitamin D were equally effective in the body. However, depending on the measuring method used, vitamin D₃ is 56-87 per cent more effective than vitamin D₂ when it comes to raising blood levels of vitamin D. Moreover, D₃ is stored in fat tissue more than three times as effectively as D₂. *

* Heaney RP, et al. Vitamin D₃ Is More Potent Than Vitamin D2 in Humans. J Clin Endocrinol Metab 2010.

Vitamin D has an array of important functions in the body. For instance, vitamin D is:

•  important for normal cell division
•  helping to maintain normal bones and teeth
•  contributing to a normal absorption and utilization of calcium and phosphorus
•  playing a role in the body's immune system and muscle function

Good vitamin D sources

Vitamin D is hardly found in plant foods, it is low in dairy products and found in highest amounts in some animal foods. Some of the best sources being:

• Oily fish
• Liver
• Cod liver
• Oils
• Eggs
• Butter

Strong vitamin-D supplements might be particularly indicated in:

• Individuals with dark pigmentation as they require 5 to 10 times more exposure to sunlight to generate same amounts of vitamin D3 as individuals with little or no pigmentation
• Anyone who, regardless of their age, are at increased risk for osteoporosis
• People who do not spend time outdoors in the daytime or generally avoid sunlight
• Adults who wear fully covering clothes in the summer time
• Nursing home residents
• People older than 70 years. An older skin is less able to generate vitamin D3 from sunlight

Vegans and vegetarians are advised to adhere to the official guidelines for sun exposure and possibly take a supplement of vitamin D during the winter period.
Blood levels of vitamin D can be determined by a blood test that measures the unit 25-hydroxyvitamin D (25-(OH)D) and is expressed in nmol/l. Vitamin D status is graduated in the following way:

• <12 nmol/l: Severe deficiency
• 12-25 nmol/l: Deficiency
• 25-50 nmol/l: Insufficient
• >50 nmol/l: Sufficient
• 75-150 nmol/l: Optimal level in individuals with fragile bones and kidney patients
• >approx. 200 nmol/l: Risk of overdose

> = greater than
< = less than

Conversion

1 nmol/l = 0,4 ng/ml

Measurement of vitamin D

The safest way to know one's vitamin D status is by means of a blood test. However, for normal, healthy individuals there is no immediate need to measure blood levels of vitamin D. For certain groups, however, it is advisable to gauge their vitamin D status.

For instance, people with a lifestyle that gives reason to believe that they could benefit from checking their status. Besides the obvious factors that limit vitamin D such as lack of sunlight and poor diet, there are more subtle causes such as the fact that some types of medicine may affect the body’s vitamin D absorption, thereby increasing the need for this particular nutrient.